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Polynucleotides
Polynucleotides are injectable treatments used to support skin regeneration, repair, and overall skin quality. Rather than adding volume or altering facial shape, polynucleotides work at a cellular level to improve hydration, elasticity, and tissue health over time.
At Harley Private Dental, polynucleotide treatments are performed by Dr Isran, ensuring a medically led, safety-focused approach based on careful assessment and appropriate patient selection.
A regenerative approach to skin health
Modern aesthetic medicine is increasingly focused on skin quality and regeneration rather than surface-level change. Polynucleotides are part of this regenerative approach, designed to support the skin’s natural repair processes and improve overall tissue quality.
Our focus is on:
- Improving skin health and resilience
- Supporting natural regeneration
- Subtle, progressive results
- Doctor-led treatment and clinical judgement
What are polynucleotides?
Polynucleotides are biologically derived molecules that play a role in tissue repair and regeneration. When injected into the skin, they help to:
- Improve skin hydration
- Support collagen production
- Enhance elasticity and texture
- Promote healthier skin function
They are not dermal fillers and do not add volume or change facial contours.
What areas can be treated?
Polynucleotides can be used in a range of areas where skin quality may be compromised, including:
- Face
- Under-eye area
- Neck
- Décolletage
- Other areas with signs of skin thinning or damage
Treatment areas are selected following consultation and skin assessment.
Who are polynucleotides suitable for?
Polynucleotide treatment may be suitable if you:
- Notice dull, dehydrated, or fragile skin
- Have early signs of ageing or skin laxity
- Want to improve skin quality without adding volume
- Prefer regenerative, non-surgical treatments
- Value doctor-led aesthetic care
Suitability is assessed during consultation, taking into account medical history, skin condition, and expectations.
How do polynucleotides differ from other injectables?
Polynucleotides differ from other aesthetic injectables in their purpose:
- Not dermal fillers – they do not create volume or contour
- Different to skin boosters – they focus on regeneration as well as hydration
- Progressive results – improvements develop gradually over time
Your clinician will advise whether polynucleotides, skin boosters, or alternative treatments are most appropriate for your concerns.
What does the treatment involve?
- Consultation and assessment
Your skin concerns, goals, and medical history are reviewed. - Treatment planning
The treatment area and protocol are planned conservatively. - Polynucleotide injections
Injections are administered carefully, with comfort and safety prioritised. - Aftercare guidance
Clear aftercare instructions are provided to support healing and results.
Treatment is usually quick, with minimal downtime.
What results can I expect?
Polynucleotides are designed to achieve:
- Improved skin hydration and texture
- Enhanced elasticity and resilience
- Healthier-looking, more robust skin over time
Results develop gradually over a series of treatments and may continue to improve as the skin regenerates.
Safety and aftercare
All polynucleotide treatments are carried out by a licensed UK GP using clinically approved products.
Aftercare guidance includes:
- What to expect immediately after treatment
- How to care for treated areas
- When to resume normal activities
- When to contact the clinic if needed
Patient safety, informed consent, and appropriate follow-up are central to every treatment.
Personalised care starts here
A consultation gives us time to understand your needs, explain your options clearly, and plan care that’s right for you.
Spread the cost of your treatment
We offer finance options through Chrysalis Finance to help make treatment costs more manageable. This allows eligible patients to spread the cost of treatment over time with clear, structured repayments. Finance is available at a representative 14.9% APR, subject to status and approval.
Our finance calculator provides an indicative example of how treatment costs may be spread into monthly payments based on a 14.9% APR. Simply enter the estimated treatment cost and select a repayment term to view a guide price. Figures shown are for illustration only. Final repayment amounts will be confirmed following consultation and finance approval.
Using the calculator does not commit you to treatment or finance. It is designed to help you understand your options clearly, without pressure. Full details, including repayment terms and eligibility, will always be explained before you proceed.
Frequently asked questions
Practical guidance to help you understand our care, treatments, and what to expect.
Do polynucleotides add volume to the face?
No. Polynucleotides are not volumising treatments. They focus on improving skin quality and regeneration rather than altering facial shape.
How many treatments are needed?
Treatment plans vary depending on skin condition and goals. This will be discussed during consultation.
Is there downtime after treatment?
Most patients experience minimal downtime. Mild redness or swelling at injection sites usually settles quickly.
Are polynucleotides safe?
When administered by a qualified medical professional using approved products, polynucleotide treatments are considered safe. All treatments at Harley Private Dental are delivered by a licensed UK GP.
Our wonderful team
Our team includes experienced general dentists and clinicians with specialist skills. Together we deliver a wide range of treatments under one roof.
Our other treatments
Medical aesthetics & wellness
Facial aesthetic treatments are designed to complement dental care by supporting facial balance and skin quality. Non-surgical options may include wrinkle management and dermal fillers, delivered with clinical precision and patient safety in mind.
Skin treatments
Skin treatments focus on improving skin health, texture, and resilience through clinically informed, non-invasive and minimally invasive therapies. Using techniques such as microneedling, topical actives, and light therapy, treatments are designed to support long-term skin quality rather than quick cosmetic fixes.